SLC22A18AS

Across TCGA cell cohorts, SLC22A18AS RNA expression is significantly associated with the go_rna of many other GO terms, with 3,431 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC22A18AS-associated GO terms across cancer lineages are Bile acid signaling pathway, Regulation of tolerance induction dependent upon immune response, and Telomeric D-loop disassembly. Each is linked with SLC22A18AS in more than 8 cancer types. Because this analysis shows association rather than direction, both SLC22A18AS-to-partner and partner-to-SLC22A18AS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Bile acid signaling pathway grouped by SLC22A18AS-low versus SLC22A18AS-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A18AS→partner) and Y-score (partner→SLC22A18AS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Bile acid signaling pathway →	-0.197	-1.557	<.001	<.001	3	9
LUNG_NSCLC_LUSC	Regulation of tolerance induction dependent upon immune response →	+1.299	+1.297	.004	.009	3	8
LIVER	Telomeric D-loop disassembly →	-0.083	-1.401	.006	.006	3	8
STOMACH	Positive regulation of transporter activity →	+0.100	+1.186	.006	.009	2	8
STOMACH	Positive regulation of toll-like receptor 4 signaling pathway →	+0.128	+1.307	.001	.001	3	7
STOMACH	Actin filament capping →	+0.145	+1.320	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,431 associations by consensus.

Bile acid signaling pathway by SLC22A18AS expression — STOMACH

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