SLC22A18AS

Across TCGA pan-cancer cohorts, SLC22A18AS RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated SLC22A18AS data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher SLC22A18AS RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated SLC22A18AS expression acts as an unfavorable survival marker, although some lineages such as KIRP and MESO show a favorable association.

KIRP, LAML, and ACC are the cancer types where SLC22A18AS RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Median	II,III,IV	0.941	0.437	.001	44	view →
LAML	DFS	Median	All	0.444	0.692	<.001	36	view →
ACC	DFS	Median	III,IV	0.261	0.621	.006	22	view →
HNSC	DFS	Tertile	All	0.256	0.451	.008	21	view →
PAAD	OS	Tertile	All	0.396	0.609	.016	19	view →
MESO	OS	Median	III,IV	0.523	0.318	.011	19	view →
THYM	DFS	Median	III,IV	1.000	0.508	.013	18	view →
GBM	OS	Median	All	0.315	0.509	<.001	18	view →
READ	OS	Quartile	IV	0.367	0.875	.005	18	view →
UCS	OS	Quartile	All	0.864	0.505	.008	14	view →
SCLC	OS	Median	III,IV	0.471	0.743	.019	10	view →
ESCA	OS	Median	All	0.629	1.000	.012	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

SLC22A18AS–KIRP (DFS)

Open the KIRP breakdown →