SLC22A16

Across TCGA patient cohorts, SLC22A16 mutation is significantly associated with the RNA expression of many other genes, with 1,925 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SLC22A16-associated genes across cancer lineages are MIR3920, RNA5SP183, and TMEM38B. Each is linked with SLC22A16 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC22A16-to-partner and partner-to-SLC22A16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3920 grouped by SLC22A16-low versus SLC22A16-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC22A16→partner) and Y-score (partner→SLC22A16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR3920 →	+0.858	+3.915	<.001	.002	3	3
STAD	RNA5SP183 →	+0.399	+4.981	.001	.002	3	3
UCEC	TMEM38B →	+0.656	+2.098	.002	.003	3	3
UCEC	ELP5 →	+0.385	+2.617	.003	<.001	3	3
UCEC	PSMC3IP →	+0.541	+2.724	.003	.003	3	3
UCEC	MED10 →	+0.422	+2.330	.002	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,925 associations by consensus.

MIR3920 by SLC22A16 expression — BRCA

Explore this box plot interactively →