SLC19A3

Across TCGA cell cohorts, SLC19A3 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC19A3-associated genes across cancer lineages are DCLK3, TACR3, and OR1N2. Each is linked with SLC19A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC19A3-to-partner and partner-to-SLC19A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DCLK3 grouped by SLC19A3-low versus SLC19A3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC19A3→partner) and Y-score (partner→SLC19A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	DCLK3 →	+0.155	+3.769	.005	.008	3	1
BLOOD_Leukemia	TACR3 →	+0.028	+4.060	<.001	.003	3	1
BLOOD_Leukemia	OR1N2 →	+0.018	+3.705	.008	.007	3	1
BLOOD_Leukemia	SOX1 →	+0.723	+4.149	<.001	.008	3	1
BLOOD_Leukemia	FIGLA →	+0.022	+4.984	<.001	.002	3	1
BLOOD_Leukemia	KHDC3L →	+0.205	+3.774	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

DCLK3 by SLC19A3 expression — BLOOD_Leukemia

Explore this box plot interactively →