SLC17A6

Across TCGA cell cohorts, SLC17A6 RNA expression is significantly associated with the go_rna of many other GO terms, with 455 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SLC17A6-associated GO terms across cancer lineages are Negative regulation of cytokine production involved in inflammatory response, Transport along microtubule, and Regulation of neuromuscular synaptic transmission. Each is linked with SLC17A6 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC17A6-to-partner and partner-to-SLC17A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cytokine production involved in inflammatory response grouped by SLC17A6-low versus SLC17A6-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC17A6→partner) and Y-score (partner→SLC17A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Negative regulation of cytokine production involved in inflammatory response →	-0.051	-1.475	.004	.007	3	3
LUNG_SCLC	Transport along microtubule →	+0.047	+1.640	.001	.002	3	2
LUNG_SCLC	Regulation of neuromuscular synaptic transmission →	+0.972	+2.581	.001	.001	3	2
LUNG_SCLC	Positive regulation of neuromuscular synaptic transmission →	+0.972	+2.581	.001	.001	3	2
LUNG_SCLC	Protein localization to cytoplasmic stress granule →	+0.118	+1.863	.002	.005	3	2
LUNG_SCLC	Ribosome-associated ubiquitin-dependent protein catabolic process →	+0.089	+2.753	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 455 associations by consensus.

Negative regulation of cytokine production involved in inflammatory response by SLC17A6 expression — LUNG_SCLC

Explore this box plot interactively →