SLC17A6

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, SLC17A6 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of SLC17A6’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where SLC17A6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SLC17A6 is over-expressed in tumor.

HNSC and KIRC are the cancer types where SLC17A6 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC17A6 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
HNSCFemaleII,III,IV+0.010.0215view →
KIRCAllAll+0.001.0451view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

SLC17A6–HNSC

Tumor-vs-normal expression box plot for SLC17A6 RNA in HNSC.

Open the HNSC breakdown →

Exploration