SLC17A6

Across TCGA cell cohorts, SLC17A6 mutation is significantly associated with the RNA expression of many other genes, with 159 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC17A6-associated genes across cancer lineages are H2BW1, SNTG2, and NDUFV2. Each is linked with SLC17A6 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC17A6-to-partner and partner-to-SLC17A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, H2BW1 grouped by SLC17A6-low versus SLC17A6-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC17A6→partner) and Y-score (partner→SLC17A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	H2BW1 →	+0.218	+3.364	<.001	<.001	3	2
LUNG_NSCLC_LUAD	SNTG2 →	+0.450	+3.142	.007	.002	3	2
LARGE_INTESTINE	NDUFV2 →	+0.542	+3.502	.006	.001	3	2
BLOOD_Leukemia	PNLIPRP2 →	+0.678	+5.539	<.001	.003	3	2
BLOOD_Lymphoma	HTR1A →	+0.016	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	KRTAP10-10 →	+0.014	+4.643	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 159 associations by consensus.

H2BW1 by SLC17A6 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →