SLC16A9

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC16A9 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible SLC16A9-associated genes across cancer lineages are MRAP, IFIT1B, and REG1B. Each is linked with SLC16A9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC16A9-to-partner and partner-to-SLC16A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MRAP grouped by SLC16A9-low versus SLC16A9-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A9→partner) and Y-score (partner→SLC16A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaMRAP →+0.073+4.807<.001.00631
BLOOD_MyelomaIFIT1B →+0.013+4.807<.001.00631
LARGE_INTESTINEREG1B →+1.926+4.196.007.00231
LARGE_INTESTINEOR10W1 →+0.019+4.562<.001<.00131
LARGE_INTESTINEC14orf180 →+0.198+4.155<.001.00331
OVARYPRM1 →+0.078+5.196<.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

MRAP by SLC16A9 expression — BLOOD_Myeloma

Box plot of MRAP in SLC16A9-low vs SLC16A9-high samples in BLOOD_Myeloma.

Explore this box plot interactively →

Exploration