SLC16A9

Across TCGA pan-cancer cohorts, SLC16A9 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of SLC16A9’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where SLC16A9 RNA is repressed in tumor relative to normal tissue. In most cancer types SLC16A9 is over-expressed in tumor, although a few such as COAD and KICH show the opposite, repressed pattern.

COAD, KICH, and LUAD are the cancer types where SLC16A9 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC16A9 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	IV	−3.000	<.001	12	view →
KICH	Female	All	−4.849	<.001	11	view →
LUAD	Male	II,III,IV	+2.330	<.001	9	view →
READ	All	II,III,IV	−3.352	<.001	7	view →
UCEC	All	II,III,IV	−2.678	<.001	6	view →
LUSC	Female	All	+1.667	<.001	6	view →
BRCA	Female	All	−0.437	<.001	6	view →
KIRP	All	III,IV	−2.315	.010	5	view →
LIHC	All	All	+0.637	.023	4	view →
THCA	Female	II,III,IV	+0.807	.007	3	view →
HNSC	All	II,III,IV	−0.725	.017	3	view →
BLCA	Male	IV	−1.627	.004	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

SLC16A9–COAD

Open the COAD breakdown →