SLC16A5

Across TCGA patient cohorts, SLC16A5 mutation is significantly associated with the RNA expression of many other genes, with 542 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC16A5-associated genes across cancer lineages are MIR4694, MIR30C1, and RNU2-15P. Each is linked with SLC16A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC16A5-to-partner and partner-to-SLC16A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4694 grouped by SLC16A5-low versus SLC16A5-high in GBM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A5→partner) and Y-score (partner→SLC16A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MIR4694 →	+0.516	+5.352	<.001	.005	3	2
GBM	MIR30C1 →	+0.485	+5.352	<.001	.005	3	2
GBM	RNU2-15P →	+0.413	+5.149	<.001	.007	3	2
COAD	ELAVL4-AS1 →	+0.128	+4.602	.001	.008	3	2
HNSC	MTATP6P30 →	+0.089	+7.954	<.001	.008	3	2
HNSC	RNU7-34P →	+0.633	+7.954	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 542 associations by consensus.

MIR4694 by SLC16A5 expression — GBM

Explore this box plot interactively →