SLC16A5

Across TCGA cell cohorts, SLC16A5 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC16A5-associated genes across cancer lineages are FTMT, HTR1E, and TFDP3. Each is linked with SLC16A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC16A5-to-partner and partner-to-SLC16A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FTMT grouped by SLC16A5-low versus SLC16A5-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A5→partner) and Y-score (partner→SLC16A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	FTMT →	+0.065	+4.977	<.001	.002	3	1
LARGE_INTESTINE	HTR1E →	+0.085	+3.930	<.001	.003	3	1
LARGE_INTESTINE	TFDP3 →	+0.035	+4.196	<.001	.002	3	1
LARGE_INTESTINE	OR2J3 →	+0.044	+3.920	<.001	.005	3	1
LARGE_INTESTINE	UBE2QL1 →	+0.345	+3.722	<.001	.007	3	1
LUNG_SCLC	FFAR3 →	+0.047	+5.029	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

FTMT by SLC16A5 expression — SOFT_TISSUE

Explore this box plot interactively →