SLC13A2

Across TCGA cell cohorts, SLC13A2 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SLC13A2-associated genes across cancer lineages are OR6F1, OR2T12, and ASPN. Each is linked with SLC13A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC13A2-to-partner and partner-to-SLC13A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6F1 grouped by SLC13A2-low versus SLC13A2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC13A2→partner) and Y-score (partner→SLC13A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR6F1 →	+0.139	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	OR2T12 →	+0.009	+4.643	<.001	.005	3	1
LARGE_INTESTINE	ASPN →	+0.037	+3.648	.002	.002	3	1
BLOOD_Leukemia	GNGT1 →	+0.060	+4.551	<.001	.004	3	1
BLOOD_Leukemia	KRTAP6-3 →	+0.187	+5.569	<.001	.001	3	1
SKIN	OR5A1 →	+0.008	+3.700	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

OR6F1 by SLC13A2 expression — BLOOD_Lymphoma

Explore this box plot interactively →