SLBP

Across TCGA patient cohorts, SLBP mutation is significantly associated with the RNA expression of many other genes, with 30 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLBP-associated genes across cancer lineages are LARP7P1, MIR6864, and OR5H5P. Each is linked with SLBP in more than 1 cancer types. Because this analysis shows association rather than direction, both SLBP-to-partner and partner-to-SLBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LARP7P1 grouped by SLBP-low versus SLBP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLBP→partner) and Y-score (partner→SLBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LARP7P1 →	+0.157	+3.771	.002	.003	3	1
UCEC	MIR6864 →	+0.722	+3.061	.006	.008	3	1
SKCM	OR5H5P →	+0.034	+7.816	<.001	.008	3	1
UCEC	SNORD82 →	+1.092	+3.776	<.001	.001	3	1
UCEC	MIR629 →	+0.360	+4.260	<.001	.007	3	1
UCEC	SNRPGP13 →	+0.262	+3.430	.007	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

LARP7P1 by SLBP expression — UCEC

Explore this box plot interactively →