SLAMF9

Across TCGA cell cohorts, SLAMF9 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,339 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLAMF9-associated GO terms across cancer lineages are Regulation of vasculature development, Negative regulation of intrinsic apoptotic signaling pathway, and Cell-substrate adhesion. Each is linked with SLAMF9 in more than 6 cancer types. Because this analysis shows association rather than direction, both SLAMF9-to-partner and partner-to-SLAMF9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of vasculature development grouped by SLAMF9-low versus SLAMF9-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLAMF9→partner) and Y-score (partner→SLAMF9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of vasculature development →	+0.092	+0.325	<.001	.007	3	6
UPPER_AERODIGESTIVE_TRACT	Negative regulation of intrinsic apoptotic signaling pathway →	+0.069	+0.879	.003	.007	2	7
LUNG_NSCLC_LUAD	Cell-substrate adhesion →	+0.074	+0.412	<.001	<.001	3	6
LUNG_NSCLC_LUAD	Wound healing →	+0.048	+0.395	.004	.001	3	6
LUNG_NSCLC_LUAD	Microtubule severing →	-0.053	-0.392	.001	.004	3	6
UPPER_AERODIGESTIVE_TRACT	Sperm flagellum assembly →	-0.046	-0.770	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,339 associations by consensus.

Regulation of vasculature development by SLAMF9 expression — BONE

Explore this box plot interactively →