SLAMF9

Across TCGA cell cohorts, SLAMF9 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLAMF9-associated genes across cancer lineages are OR7A17, DAZ3, and DEFA3. Each is linked with SLAMF9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLAMF9-to-partner and partner-to-SLAMF9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR7A17 grouped by SLAMF9-low versus SLAMF9-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLAMF9→partner) and Y-score (partner→SLAMF9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR7A17 →	+0.009	+4.415	<.001	.007	3	1
LARGE_INTESTINE	DAZ3 →	+0.020	+5.022	<.001	.002	3	1
LARGE_INTESTINE	DEFA3 →	+0.076	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR7A17 by SLAMF9 expression — LARGE_INTESTINE

Explore this box plot interactively →