SKIV2L

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SKIV2L mutation is significantly associated with the RNA expression of many other genes, with 2,451 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SKIV2L-associated genes across cancer lineages are OR2Z1, RNU6-622P, and TUBB4BP4. Each is linked with SKIV2L in more than 2 cancer types. Because this analysis shows association rather than direction, both SKIV2L-to-partner and partner-to-SKIV2L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SKIV2L→partner) and Y-score (partner→SKIV2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIHCOR2Z1 →+0.090+6.129<.001<.00133
HNSCRNU6-622P →+0.233+3.956<.001.00933
COADTUBB4BP4 →+0.062+4.734<.001.00233
UCECZNF25-DT →+0.092+1.542.006.00833
SKCMAAR2 →-0.307-2.651.007.00633
SKCMMTND4LP7 →+0.056+1.988.002.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,451 associations by consensus.

Exploration