SKAP1

Across TCGA patient cohorts, SKAP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,543 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SKAP1-associated proteins across cancer lineages are SEPTIN1, SEPTIN1_S206, and SEPTIN6. Each is linked with SKAP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both SKAP1-to-partner and partner-to-SKAP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SKAP1 versus SEPTIN1 in HNSC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SKAP1→partner) and Y-score (partner→SKAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SEPTIN1 →	+0.813	+0.951	<.001	<.001	3	7
HNSC	SEPTIN1_S206 →	+1.054	+0.859	<.001	.003	3	7
HNSC	SEPTIN6 →	+0.547	+1.083	<.001	<.001	3	6
HNSC	STAT5A →	+0.509	+1.206	<.001	<.001	3	5
HNSC	ADPRH →	+0.392	+0.925	<.001	<.001	3	5
HNSC	CORO1A →	+0.577	+0.838	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,543 associations by consensus.

SKAP1 vs SEPTIN1 — HNSC

Explore this scatter interactively →