SKAP1-AS1

Across TCGA pan-cancer cohorts, SKAP1-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated SKAP1-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher SKAP1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SKAP1-AS1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and LUSC show a favorable association.

KIRC, ACC, and BLCA are the cancer types where SKAP1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.524	0.707	<.001	132	view →
ACC	OS	Tertile	III,IV	0.255	0.762	<.001	80	view →
BLCA	OS	Quartile	All	0.556	0.280	.002	37	view →
DLBC	DFS	Tertile	All	0.327	0.893	.001	35	view →
LUSC	DFS	Tertile	III,IV	0.782	0.432	.002	34	view →
BRCA	DFS	Median	All	0.575	0.480	.004	28	view →
PCPG	DFS	Tertile	All	0.583	0.926	<.001	24	view →
THCA	OS	Tertile	IV	0.455	0.838	.005	15	view →
STAD	OS	Median	II,III,IV	0.726	0.435	.014	15	view →
KIRP	DFS	Median	IV	0.041	0.621	.012	12	view →
MESO	OS	Median	IV	0.301	0.674	.021	12	view →
THYM	DFS	Tertile	IV	0.407	1.000	.026	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

SKAP1-AS1–KIRC (DFS)

Open the KIRC breakdown →