SKAP1-AS1

Across TCGA pan-cancer cohorts, SKAP1-AS1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of SKAP1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in cholangiocarcinoma (CHOL), where SKAP1-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SKAP1-AS1 is over-expressed in tumor, although a few such as KICH and LUSC show the opposite, repressed pattern.

CHOL, COAD, and BRCA are the cancer types where SKAP1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SKAP1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
CHOL	All	All	+0.203	.001	5	view →
COAD	All	II,III,IV	+0.139	.003	5	view →
BRCA	All	All	+0.129	.014	4	view →
STAD	All	All	+0.488	.002	3	view →
READ	Female	All	+0.438	.018	2	view →
KICH	Female	All	−0.169	.004	2	view →
LUSC	Male	All	−0.109	.009	2	view →
THCA	All	All	−0.085	.014	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

SKAP1-AS1–CHOL

Open the CHOL breakdown →