SIK3-IT1

Across TCGA patient cohorts, SIK3-IT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,093 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SIK3-IT1-associated GO terms across cancer lineages are Regulation of translational initiation, Obsolete histone methylation, and Protein autoubiquitination. Each is linked with SIK3-IT1 in more than 29 cancer types. Because this analysis shows association rather than direction, both SIK3-IT1-to-partner and partner-to-SIK3-IT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of translational initiation grouped by SIK3-IT1-low versus SIK3-IT1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SIK3-IT1→partner) and Y-score (partner→SIK3-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of translational initiation →	+0.074	+0.350	<.001	<.001	3	30
STAD	Obsolete histone methylation →	+0.075	+0.349	<.001	<.001	3	30
STAD	Protein autoubiquitination →	+0.060	+0.318	<.001	<.001	3	30
STAD	Peptidyl-serine autophosphorylation →	+0.091	+0.336	<.001	<.001	3	30
STAD	Regulation of mRNA catabolic process →	+0.055	+0.342	<.001	<.001	3	29
STAD	Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway →	+0.061	+0.344	<.001	<.001	3	29

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,093 associations by consensus.

Regulation of translational initiation by SIK3-IT1 expression — STAD

Explore this box plot interactively →