SIGLEC24P

Q-omics provides the consensus-scored SIGLEC24P profile across patient tissues and cancer cell-line models. SIGLEC24P expression is associated with patient survival in 11 of 34 cancer types, with the highest sampling consensus in KIRC. Additionally, SIGLEC24P RNA expression shows 6,140 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight KIRC, and STAD as cancer lineages where SIGLEC24P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes SIGLEC24P survival associations across molecular data types. SIGLEC24P RNA expression shows survival associations in the most cancer types (11). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

SIGLEC24P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	11	KIRC (72)	view →

This table ranks reproducible SIGLEC24P RNA expression–survival associations across cancer types. High SIGLEC24P expression shows unfavorable associations in KIRC, LIHC, THCA, GBM, CHOL and SKCM. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .008). Together, the overview and detailed table identify KIRC as the clearest survival context for SIGLEC24P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.750	0.814	.008	72	view →
LIHC	OS	Tertile	III,IV	0.059	0.738	<.001	66	view →
THCA	DFS	Tertile	IV	0.126	0.805	.002	57	view →
GBM	DFS	Tertile	All	0.080	0.260	.002	36	view →
CHOL	OS	Tertile	All	0.089	0.727	.001	27	view →
SKCM	DFS	Tertile	All	0.078	0.213	.004	18	view →

Pink = unfavorable, green = favorable. all 11 lineages →

SIGLEC24P-KIRC (OS)

Explore this curve interactively →