SI

Across TCGA cell cohorts, SI protein abundance is significantly associated with the RNA expression of many other genes, with 1,462 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SI-associated genes across cancer lineages are RANGRF, ZNF567, and DCTD. Each is linked with SI in more than 4 cancer types. Because this analysis shows association rather than direction, both SI-to-partner and partner-to-SI results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SI versus RANGRF in BLOOD_Leukemia, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SI→partner) and Y-score (partner→SI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	RANGRF →	+1.275	+1.742	<.001	<.001	3	5
BLOOD_Lymphoma	ZNF567 →	+0.801	+0.759	.007	.006	3	4
STOMACH	DCTD →	-0.876	-1.746	.002	<.001	3	4
LIVER	MNX1 →	+2.403	+1.953	.004	.005	3	3
LIVER	MYLK4 →	-0.180	-1.953	.006	.005	3	3
LARGE_INTESTINE	BTC →	-1.168	-1.144	.004	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,462 associations by consensus.

SI vs RANGRF — BLOOD_Leukemia

Explore this scatter interactively →