SHQ1

Across TCGA patient cohorts, SHQ1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,713 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SHQ1-associated proteins across cancer lineages are QRICH1, RRP9, and MCM2_S27. Each is linked with SHQ1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SHQ1-to-partner and partner-to-SHQ1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SHQ1 versus QRICH1 in PDAC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SHQ1→partner) and Y-score (partner→SHQ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	QRICH1 →	+0.204	+0.330	<.001	<.001	3	5
GBM	RRP9 →	+0.429	+0.323	<.001	<.001	3	4
LUAD	MCM2_S27 →	+0.629	+0.239	.001	.005	3	4
OV	MYG1 →	+0.431	+0.525	.001	<.001	3	4
BRCA	IRF4 →	-0.920	-0.670	<.001	<.001	3	4
BRCA	ISG20 →	-0.564	-0.420	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,713 associations by consensus.

SHQ1 vs QRICH1 — PDAC

Explore this scatter interactively →