Across TCGA cell cohorts, SHPK RNA expression is significantly associated with the go_rna of many other GO terms, with 4,582 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SHPK-associated GO terms across cancer lineages are Establishment of spindle localization, Spindle localization, and Nucleosome disassembly. Each is linked with SHPK in more than 12 cancer types. Because this analysis shows association rather than direction, both SHPK-to-partner and partner-to-SHPK results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SHPK→partner) and Y-score (partner→SHPK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Establishment of spindle localization →	+0.134	+0.891	<.001	.004	3	13
PANCREAS	Spindle localization →	+0.121	+0.790	<.001	<.001	3	13
PANCREAS	Nucleosome disassembly →	+0.136	+0.732	<.001	.001	3	13
CNS	Pyrimidine deoxyribonucleoside monophosphate biosynthetic process →	+0.140	+0.809	<.001	<.001	3	13
CNS	DTMP biosynthetic process →	+0.140	+0.809	<.001	<.001	3	13
OVARY	Positive regulation of mitotic cytokinesis →	+0.148	+0.967	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,582 associations by consensus.

Exploration

SHPK survival (RNA) · tumor vs normal (RNA) · all SHPK data types