Across TCGA patient cohorts, SHCBP1L RNA expression is significantly associated with the go_rna of many other GO terms, with 6,935 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SHCBP1L-associated GO terms across cancer lineages are Chaperone-mediated protein folding, Protein stabilization, and Signal transduction by p53 class mediator. Each is linked with SHCBP1L in more than 14 cancer types. Because this analysis shows association rather than direction, both SHCBP1L-to-partner and partner-to-SHCBP1L results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SHCBP1L→partner) and Y-score (partner→SHCBP1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Chaperone-mediated protein folding →	+0.079	+0.213	<.001	.001	3	15
STAD	Protein stabilization →	+0.067	+0.186	<.001	<.001	3	13
ESCA	Signal transduction by p53 class mediator →	+0.091	+0.246	<.001	<.001	3	13
STAD	Regulation of post-translational protein modification →	+0.066	+0.185	<.001	<.001	3	13
STAD	Cellular respiration →	+0.071	+0.203	<.001	<.001	3	13
STAD	Apoptotic mitochondrial changes →	+0.059	+0.206	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,935 associations by consensus.

Exploration

SHCBP1L survival (RNA) · tumor vs normal (RNA) · all SHCBP1L data types