SH3PXD2A

Across TCGA patient cohorts, SH3PXD2A RNA expression is significantly associated with the protein abundance of many other proteins, with 14,087 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SH3PXD2A-associated proteins across cancer lineages are COL5A1, ISLR, and LRP1. Each is linked with SH3PXD2A in more than 8 cancer types. Because this analysis shows association rather than direction, both SH3PXD2A-to-partner and partner-to-SH3PXD2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH3PXD2A versus COL5A1 in OV, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3PXD2A→partner) and Y-score (partner→SH3PXD2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	COL5A1 →	+0.637	+1.157	<.001	<.001	3	9
LSCC	ISLR →	+0.688	+0.687	<.001	<.001	3	8
OV	LRP1 →	+0.508	+1.227	<.001	<.001	3	8
LSCC	MMP2 →	+0.811	+0.611	<.001	<.001	3	8
BRCA	PCOLCE →	+0.932	+1.043	<.001	<.001	3	8
BRCA	COL5A2 →	+1.097	+0.887	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,087 associations by consensus.

SH3PXD2A vs COL5A1 — OV

Explore this scatter interactively →