SH3GLB1

Across TCGA patient cohorts, SH3GLB1 protein abundance is significantly associated with the RNA expression of many other genes, with 19,941 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SH3GLB1-associated genes across cancer lineages are ANTXR2, SKA3, and GINS1. Each is linked with SH3GLB1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SH3GLB1-to-partner and partner-to-SH3GLB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH3GLB1 versus ANTXR2 in UCEC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3GLB1→partner) and Y-score (partner→SH3GLB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ANTXR2 →	+0.833	+0.249	<.001	.001	3	6
UCEC	SKA3 →	-1.000	-0.306	<.001	<.001	3	6
UCEC	GINS1 →	-1.221	-0.302	<.001	<.001	3	5
UCEC	FAM83D →	-1.162	-0.267	<.001	.001	3	5
UCEC	SFXN3 →	+0.842	+0.303	<.001	<.001	3	5
HNSC	TMEM97 →	-1.154	-0.220	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,941 associations by consensus.

SH3GLB1 vs ANTXR2 — UCEC

Explore this scatter interactively →