SH3D19

Across TCGA patient cohorts, SH3D19 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,935 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SH3D19-associated proteins across cancer lineages are PPFIBP1, SEPTIN11, and GUCY1B1. Each is linked with SH3D19 in more than 6 cancer types. Because this analysis shows association rather than direction, both SH3D19-to-partner and partner-to-SH3D19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH3D19 versus PPFIBP1 in BRCA, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3D19→partner) and Y-score (partner→SH3D19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PPFIBP1 →	+0.397	+0.860	<.001	<.001	3	7
BRCA	SEPTIN11 →	+0.333	+0.896	<.001	<.001	3	7
OV	GUCY1B1 →	+0.532	+1.056	<.001	<.001	3	7
LUAD	MKI67_S357 →	-1.080	-0.496	.001	<.001	3	7
BRCA	TOM1L2 →	+0.443	+0.963	<.001	<.001	3	6
OV	PPP1R12C →	+0.346	+0.918	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,935 associations by consensus.

SH3D19 vs PPFIBP1 — BRCA

Explore this scatter interactively →