SH3BP1

Across TCGA patient cohorts, SH3BP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,340 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SH3BP1-associated proteins across cancer lineages are SKAP2, DOCK2, and MYO1G. Each is linked with SH3BP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both SH3BP1-to-partner and partner-to-SH3BP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH3BP1 versus SKAP2 in OV, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3BP1→partner) and Y-score (partner→SH3BP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SKAP2 →	+0.647	+0.613	<.001	.003	3	7
OV	DOCK2 →	+0.549	+0.480	.005	.002	3	7
OV	MYO1G →	+0.499	+0.735	<.001	<.001	3	7
OV	WIPF1 →	+0.443	+0.547	.005	<.001	3	6
GBM	INPP5D →	+0.523	+0.347	<.001	<.001	3	6
OV	LCP2 →	+0.478	+0.654	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,340 associations by consensus.

SH3BP1 vs SKAP2 — OV

Explore this scatter interactively →