SH2D4B

RNA expression — cross-omics
Cross-omicsRNA → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SH2D4B RNA expression is significantly associated with the RNA expression of many other genes, with 4,308 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SH2D4B-associated genes across cancer lineages are DYDC2, WBP2NL, and SFT2D2. Each is linked with SH2D4B in more than 3 cancer types. Because this analysis shows association rather than direction, both SH2D4B-to-partner and partner-to-SH2D4B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH2D4B versus DYDC2 in OVARY, with a Pearson correlation of 0.48.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SH2D4B→partner) and Y-score (partner→SH2D4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYDYDC2 →+0.789+0.081.001<.00134
OVARYWBP2NL →+0.660+0.080<.001<.00133
OVARYSFT2D2 →+0.622+0.059<.001<.00133
OVARYKIAA0040 →+1.713+0.057<.001<.00133
OVARYENDOU →+1.221+0.082.001<.00133
OVARYPRDM2 →+0.822+0.097.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,308 associations by consensus.

SH2D4B vs DYDC2 — OVARY

Per-sample scatter of SH2D4B vs DYDC2 in OVARY (Pearson r = 0.48).

Explore this scatter interactively →

Exploration