SH2D3C

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SH2D3C RNA expression is significantly associated with the protein abundance of many other proteins, with 21,976 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SH2D3C-associated proteins across cancer lineages are ARHGAP45, AIF1, and EVL. Each is linked with SH2D3C in more than 8 cancer types. Because this analysis shows association rather than direction, both SH2D3C-to-partner and partner-to-SH2D3C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH2D3C versus ARHGAP45 in OV, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SH2D3C→partner) and Y-score (partner→SH2D3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARHGAP45 →+0.645+0.987<.001<.00139
HNSCAIF1 →+0.630+0.687<.001<.00139
UCECEVL →+0.672+0.693<.001<.00139
LSCCGIMAP8 →+0.574+0.721<.001<.00139
CCRCCRASIP1 →+0.641+0.934<.001<.00139
HNSCSTAB1 →+0.475+0.567<.001.00439
Each partner links to its Q-omics profile. Showing the 6 strongest of 21,976 associations by consensus.

SH2D3C vs ARHGAP45 — OV

Per-sample scatter of SH2D3C vs ARHGAP45 in OV (Pearson r = 0.50).

Explore this scatter interactively →

Exploration