SGO1

Across TCGA patient cohorts, SGO1 RNA expression is significantly associated with the protein abundance of many other proteins, with 27,032 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SGO1-associated proteins across cancer lineages are RRM2, SETDB1_S1066, and SMC2. Each is linked with SGO1 in more than 9 cancer types. Because this analysis shows association rather than direction, both SGO1-to-partner and partner-to-SGO1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SGO1 versus RRM2 in LUAD, with a Pearson correlation of 0.69.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SGO1→partner) and Y-score (partner→SGO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RRM2 →	+1.039	+0.878	<.001	<.001	3	10
BRCA	SETDB1_S1066 →	+1.092	+0.923	<.001	<.001	3	10
LUAD	SMC2 →	+0.765	+0.922	<.001	<.001	3	10
LUAD	SMC4 →	+0.749	+0.902	<.001	<.001	3	10
UCEC	MAD2L1 →	+0.506	+0.966	<.001	<.001	3	10
LUAD	NCAPG_S674 →	+1.414	+0.837	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 27,032 associations by consensus.

SGO1 vs RRM2 — LUAD

Explore this scatter interactively →