Across TCGA patient cohorts, SETP8 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,970 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SETP8-associated proteins across cancer lineages are SPIN1, NRF1_S136, and TOP2A_S1377. Each is linked with SETP8 in more than 3 cancer types. Because this analysis shows association rather than direction, both SETP8-to-partner and partner-to-SETP8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SETP8→partner) and Y-score (partner→SETP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SPIN1 →	+0.457	+0.303	<.001	<.001	3	4
OV	NRF1_S136 →	+1.130	+1.611	.004	.001	3	4
LSCC	TOP2A_S1377 →	+0.872	+0.276	<.001	<.001	3	4
OV	PRRC2B_S613 →	+0.914	+1.319	<.001	<.001	3	4
LSCC	DDX47 →	+0.384	+0.350	<.001	<.001	3	4
LSCC	ZNHIT6_S25 →	+0.529	+0.298	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,970 associations by consensus.

Exploration

SETP8 survival (RNA) · tumor vs normal (RNA) · all SETP8 data types