SETP16

Across TCGA patient cohorts, SETP16 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,717 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SETP16-associated GO terms across cancer lineages are Protein folding, ER-nucleus signaling pathway, and RNA modification. Each is linked with SETP16 in more than 13 cancer types. Because this analysis shows association rather than direction, both SETP16-to-partner and partner-to-SETP16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein folding grouped by SETP16-low versus SETP16-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SETP16→partner) and Y-score (partner→SETP16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Protein folding →	+0.070	+0.169	<.001	.001	3	14
ESCA	ER-nucleus signaling pathway →	+0.083	+0.154	<.001	.003	3	14
STAD	RNA modification →	+0.064	+0.148	<.001	<.001	3	14
ESCA	RNA 3'-end processing →	+0.079	+0.178	<.001	<.001	3	14
ESCA	Regulation of RNA splicing →	+0.084	+0.175	<.001	.001	3	14
STAD	Nucleotide-excision repair →	+0.058	+0.153	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,717 associations by consensus.

Protein folding by SETP16 expression — ESCA

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