Q-omics provides the consensus-scored SERPINE4P profile across patient tissues and cancer cell-line models. SERPINE4P expression is associated with patient survival in 10 of 34 cancer types, with the highest sampling consensus in READ. Additionally, SERPINE4P RNA expression shows 10,711 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight READ, and GBM as cancer lineages where SERPINE4P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes SERPINE4P survival associations across molecular data types. SERPINE4P RNA expression shows survival associations in the most cancer types (10). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

SERPINE4P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	10	READ (66)	view →

This table ranks reproducible SERPINE4P RNA expression–survival associations across cancer types. High SERPINE4P expression shows unfavorable associations in READ, LGG, HNSC, KIRP and KIRC, but favorable associations in SKCM. The READ Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify READ as the clearest survival context for SERPINE4P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Tertile	All	0.527	0.942	<.001	66	view →
SKCM	OS	Tertile	All	0.941	0.857	.006	36	view →
LGG	DFS	Tertile	All	0.215	0.738	<.001	30	view →
HNSC	OS	Tertile	All	0.280	0.605	.040	27	view →
KIRP	DFS	Tertile	All	0.825	0.931	.006	18	view →
KIRC	DFS	Tertile	IV	0.127	0.630	.039	18	view →

Pink = unfavorable, green = favorable. all 10 lineages →

SERPINE4P-READ (OS)

Kaplan–Meier survival curve for SERPINE4P RNA expression in READ: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with SERPINE4P in patient tissues and cancer cell lines. In patient samples, SERPINE4P shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Protein (mass-spec)	10,711	GBM (6284)	view →
RNA	4,873	PCPG (1456)	view →