SERPINE4P

Across TCGA pan-cancer cohorts, SERPINE4P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated SERPINE4P data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher SERPINE4P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SERPINE4P expression acts as an unfavorable survival marker, although some lineages such as SKCM and ESCA show a favorable association.

READ, SKCM, and LGG are the cancer types where SERPINE4P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Tertile	All	0.527	0.942	<.001	66	view →
SKCM	OS	Tertile	All	0.941	0.857	.006	36	view →
LGG	DFS	Tertile	All	0.215	0.738	<.001	30	view →
HNSC	OS	Tertile	All	0.280	0.605	.040	27	view →
KIRC	DFS	Tertile	IV	0.127	0.630	.039	18	view →
KIRP	DFS	Tertile	All	0.825	0.931	.006	18	view →
ESCA	DFS	Tertile	II,III,IV	0.722	0.328	.026	9	view →
LUAD	DFS	Tertile	II,III,IV	0.315	0.724	.018	9	view →
PCPG	DFS	Tertile	All	0.682	0.944	.005	9	view →
BRCA	OS	Tertile	II,III,IV	0.802	0.915	.044	6	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

SERPINE4P–READ (OS)

Open the READ breakdown →