SERPINB9

Across TCGA patient cohorts, SERPINB9 mutation is significantly associated with the RNA expression of many other genes, with 1,196 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SERPINB9-associated genes across cancer lineages are RNU1-17P, LINC02563, and EN2. Each is linked with SERPINB9 in more than 2 cancer types. Because this analysis shows association rather than direction, both SERPINB9-to-partner and partner-to-SERPINB9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-17P grouped by SERPINB9-low versus SERPINB9-high in ESCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB9→partner) and Y-score (partner→SERPINB9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	RNU1-17P →	+0.452	+5.068	<.001	.008	3	3
BRCA	LINC02563 →	+0.206	+5.442	<.001	.002	3	2
UCEC	EN2 →	+1.462	+2.662	<.001	<.001	3	2
UCEC	ENTR1 →	+0.428	+1.808	.001	.008	3	2
UCEC	KATNAL2 →	-0.840	-2.630	<.001	<.001	3	2
UCEC	DAPK3 →	+0.534	+3.354	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,196 associations by consensus.

RNU1-17P by SERPINB9 expression — ESCA

Explore this box plot interactively →