Across TCGA cell cohorts, SERPINA5 mutation is significantly associated with the mutation status of many other genes, with 1,316 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SERPINA5-associated genes across cancer lineages are EFCAB1, PCDH1, and ASB11. Each is linked with SERPINA5 in more than 2 cancer types. Because this analysis shows association rather than direction, both SERPINA5-to-partner and partner-to-SERPINA5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINA5→partner) and Y-score (partner→SERPINA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	EFCAB1 →	+5.894	+5.321	.002	.002	1	3
LUNG_NSCLC_LUAD	PCDH1 →	+3.266	+3.266	.002	.002	1	3
BLOOD_Leukemia	ASB11 →	+4.894	+4.894	.004	.004	1	3
BLOOD_Leukemia	GPC5 →	+4.479	+5.635	<.001	<.001	1	3
BLOOD_Leukemia	ITPRID1 →	+4.309	+4.560	.007	.007	1	3
BLOOD_Leukemia	SPPL2C →	+4.309	+4.560	.007	.007	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,316 associations by consensus.

Exploration

SERPINA5 survival (RNA) · tumor vs normal (RNA) · all SERPINA5 data types