SERF1A

Across TCGA cell cohorts, SERF1A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,544 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible SERF1A-associated GO terms across cancer lineages are Protein localization to non-motile cilium, Purkinje myocyte action potential, and Membrane depolarization during Purkinje myocyte cell action potential. Each is linked with SERF1A in more than 7 cancer types. Because this analysis shows association rather than direction, both SERF1A-to-partner and partner-to-SERF1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to non-motile cilium grouped by SERF1A-low versus SERF1A-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERF1A→partner) and Y-score (partner→SERF1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Protein localization to non-motile cilium →	+0.102	+1.094	.002	.002	3	8
LUNG_NSCLC_LUSC	Purkinje myocyte action potential →	-0.858	-0.935	.003	<.001	3	8
LUNG_NSCLC_LUSC	Membrane depolarization during Purkinje myocyte cell action potential →	-0.858	-0.935	.003	<.001	3	8
PANCREAS	Establishment of meiotic spindle orientation →	+0.167	+0.786	<.001	<.001	3	7
SOFT_TISSUE	Regulation of ERK1 and ERK2 cascade →	-0.068	-0.881	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Regulation of G2/MI transition of meiotic cell cycle →	+0.100	+0.734	.004	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,544 associations by consensus.

Protein localization to non-motile cilium by SERF1A expression — OESOPHAGUS

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