SEPTIN9-DT

Across TCGA patient cohorts, SEPTIN9-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 8,344 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SEPTIN9-DT-associated proteins across cancer lineages are PTGIS, RAB27B, and PPP2R1B. Each is linked with SEPTIN9-DT in more than 3 cancer types. Because this analysis shows association rather than direction, both SEPTIN9-DT-to-partner and partner-to-SEPTIN9-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEPTIN9-DT versus PTGIS in PDAC, with a Pearson correlation of -0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPTIN9-DT→partner) and Y-score (partner→SEPTIN9-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PTGIS →	-0.563	-0.436	<.001	<.001	3	3
BRCA	RAB27B →	+0.890	+0.390	<.001	.008	3	3
HNSC	PPP2R1B →	+0.345	+0.500	.002	.003	3	3
PDAC	PSMC2 →	+0.149	+0.344	.002	<.001	3	3
LSCC	SPCS3 →	-0.410	-0.294	<.001	<.001	3	3
PDAC	ACAA1 →	+0.359	+0.349	.002	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,344 associations by consensus.

SEPTIN9-DT vs PTGIS — PDAC

Explore this scatter interactively →