SEPTIN7P9

Across TCGA patient cohorts, SEPTIN7P9 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SEPTIN7P9-associated genes across cancer lineages are RNU6-271P, GTF3C6P1, and SFPQP1. Each is linked with SEPTIN7P9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SEPTIN7P9-to-partner and partner-to-SEPTIN7P9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-271P grouped by SEPTIN7P9-low versus SEPTIN7P9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPTIN7P9→partner) and Y-score (partner→SEPTIN7P9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-271P →	+0.685	+4.852	<.001	.006	3	1
UCEC	GTF3C6P1 →	+0.406	+4.188	<.001	.009	3	1
UCEC	SFPQP1 →	+0.078	+4.326	.003	.007	3	1
UCEC	RPS27P5 →	+0.537	+4.694	<.001	.007	3	1
UCEC	RN7SL554P →	+0.326	+4.771	<.001	.006	3	1
UCEC	LSM3P4 →	+0.458	+4.661	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

RNU6-271P by SEPTIN7P9 expression — UCEC

Explore this box plot interactively →