SEPTIN7P9

Across TCGA pan-cancer cohorts, SEPTIN7P9 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated SEPTIN7P9 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SEPTIN7P9 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated SEPTIN7P9 expression acts as an unfavorable survival marker, although some lineages such as HNSC and STAD show a favorable association.

HNSC, STAD, and ACC are the cancer types where SEPTIN7P9 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	IV	0.741	0.513	<.001	108	view →
STAD	DFS	Tertile	III,IV	0.813	0.437	.001	73	view →
ACC	DFS	Quartile	All	0.289	0.800	<.001	65	view →
KIRC	OS	Median	All	0.540	0.744	<.001	40	view →
THCA	OS	Quartile	All	0.942	0.990	.009	39	view →
SKCM	OS	Tertile	All	0.430	0.306	.005	38	view →
READ	OS	Median	All	0.819	0.306	.008	20	view →
OV	DFS	Quartile	IV	0.347	0.598	.011	18	view →
COAD	OS	Median	All	0.431	0.665	.007	16	view →
BLCA	OS	Tertile	All	0.768	0.645	.008	14	view →
PAAD	OS	Quartile	All	0.570	0.270	.006	12	view →
PCPG	DFS	Quartile	All	0.963	0.792	.014	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

SEPTIN7P9–HNSC (DFS)

Open the HNSC breakdown →