SEPTIN7P11

Across TCGA patient cohorts, SEPTIN7P11 mutation is significantly associated with the RNA expression of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SEPTIN7P11-associated genes across cancer lineages are RNU4-56P, RNU6-886P, and MIR147A. Each is linked with SEPTIN7P11 in more than 1 cancer types. Because this analysis shows association rather than direction, both SEPTIN7P11-to-partner and partner-to-SEPTIN7P11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4-56P grouped by SEPTIN7P11-low versus SEPTIN7P11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPTIN7P11→partner) and Y-score (partner→SEPTIN7P11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU4-56P →	+0.286	+4.582	.006	.005	3	1
UCEC	RNU6-886P →	+0.651	+3.488	<.001	.008	3	1
UCEC	MIR147A →	+0.331	+4.582	<.001	.005	3	1
UCEC	RPL23AP4 →	+0.152	+3.717	<.001	.005	3	1
UCEC	NDUFA3P3 →	+0.256	+3.418	.002	.009	3	1
UCEC	SC4MOP →	+0.075	+4.453	.004	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

RNU4-56P by SEPTIN7P11 expression — UCEC

Explore this box plot interactively →