SEMA4F

Across TCGA cell cohorts, SEMA4F RNA expression is significantly associated with the go_rna of many other GO terms, with 5,251 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SEMA4F-associated GO terms across cancer lineages are Cytoskeleton-dependent cytokinesis, Cytokinesis, and Mitotic cytokinesis. Each is linked with SEMA4F in more than 17 cancer types. Because this analysis shows association rather than direction, both SEMA4F-to-partner and partner-to-SEMA4F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoskeleton-dependent cytokinesis grouped by SEMA4F-low versus SEMA4F-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEMA4F→partner) and Y-score (partner→SEMA4F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cytoskeleton-dependent cytokinesis →	+0.106	+1.077	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Cytokinesis →	+0.105	+1.077	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Mitotic cytokinesis →	+0.119	+1.280	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Cell division →	+0.088	+0.930	<.001	<.001	3	17
STOMACH	Regulation of cell-substrate junction organization →	+0.098	+1.023	.002	.006	3	14
CNS	Heparan sulfate proteoglycan metabolic process →	+0.090	+0.997	.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,251 associations by consensus.

Cytoskeleton-dependent cytokinesis by SEMA4F expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →