SEMA3F

Across TCGA patient cohorts, SEMA3F protein abundance is significantly associated with the RNA expression of many other genes, with 5,698 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SEMA3F-associated genes across cancer lineages are ECE1, PLK2, and SLC9A3R1. Each is linked with SEMA3F in more than 2 cancer types. Because this analysis shows association rather than direction, both SEMA3F-to-partner and partner-to-SEMA3F results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEMA3F versus ECE1 in CCRCC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEMA3F→partner) and Y-score (partner→SEMA3F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ECE1 →	+0.707	+0.362	.001	.008	3	3
BRCA	PLK2 →	+1.006	+0.489	<.001	<.001	3	3
HNSC	SLC9A3R1 →	+0.996	+0.552	<.001	.001	3	3
UCEC	ZNF267 →	-0.544	-0.569	.001	<.001	3	3
LUAD	RASSF4 →	-0.612	-0.453	<.001	<.001	3	3
BRCA	LYPD6B →	+1.184	+0.487	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,698 associations by consensus.

SEMA3F vs ECE1 — CCRCC

Explore this scatter interactively →