SEMA3F

Across TCGA patient cohorts, SEMA3F mutation is significantly associated with the RNA expression of many other genes, with 2,508 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SEMA3F-associated genes across cancer lineages are ZCCHC9, ERI1, and TSPY26P. Each is linked with SEMA3F in more than 3 cancer types. Because this analysis shows association rather than direction, both SEMA3F-to-partner and partner-to-SEMA3F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZCCHC9 grouped by SEMA3F-low versus SEMA3F-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEMA3F→partner) and Y-score (partner→SEMA3F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ZCCHC9 →	+0.458	+1.963	.005	.008	3	4
COAD	ERI1 →	+0.703	+3.196	<.001	.009	3	4
UCEC	TSPY26P →	-0.757	-2.959	.001	.001	3	4
STAD	BCAS2 →	+0.398	+3.203	.006	.009	3	4
SKCM	RASSF1-AS1 →	+0.306	+1.925	.005	.009	3	3
COAD	GSR →	+0.636	+3.459	.003	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,508 associations by consensus.

ZCCHC9 by SEMA3F expression — SKCM

Explore this box plot interactively →