SEMA3F

Across TCGA cell cohorts, SEMA3F RNA expression is significantly associated with the go_rna of many other GO terms, with 3,511 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SEMA3F-associated GO terms across cancer lineages are Negative regulation of mRNA catabolic process, Regulation of nucleotide-excision repair, and Protein destabilization. Each is linked with SEMA3F in more than 10 cancer types. Because this analysis shows association rather than direction, both SEMA3F-to-partner and partner-to-SEMA3F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mRNA catabolic process grouped by SEMA3F-low versus SEMA3F-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEMA3F→partner) and Y-score (partner→SEMA3F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of mRNA catabolic process →	+0.075	+2.263	<.001	<.001	3	11
STOMACH	Regulation of nucleotide-excision repair →	+0.121	+1.915	.001	.001	3	9
UPPER_AERODIGESTIVE_TRACT	Protein destabilization →	+0.096	+1.184	.001	.009	3	8
OESOPHAGUS	Regulation of myoblast fusion →	+0.089	+1.482	.002	.001	3	8
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.105	+1.527	.002	.001	3	8
KIDNEY	Negative regulation of mRNA splicing, via spliceosome →	+0.065	+1.250	.003	.009	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,511 associations by consensus.

Negative regulation of mRNA catabolic process by SEMA3F expression — OVARY

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