SEMA3D

Across TCGA patient cohorts, SEMA3D RNA expression is significantly associated with the protein abundance of many other proteins, with 14,619 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SEMA3D-associated proteins across cancer lineages are ANTXR1, C1orf198, and CD248. Each is linked with SEMA3D in more than 6 cancer types. Because this analysis shows association rather than direction, both SEMA3D-to-partner and partner-to-SEMA3D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEMA3D versus ANTXR1 in BRCA, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SEMA3D→partner) and Y-score (partner→SEMA3D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ANTXR1 →	+0.755	+0.881	<.001	<.001	3	7
GBM	C1orf198 →	+0.512	+1.035	<.001	<.001	3	6
OV	CD248 →	+0.869	+1.563	<.001	<.001	3	6
BRCA	COL1A2 →	+0.803	+0.974	<.001	<.001	3	6
COAD	DIP2C →	+0.468	+0.579	<.001	.006	2	7
OV	ITGB5 →	+0.810	+1.596	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,619 associations by consensus.

SEMA3D vs ANTXR1 — BRCA

Explore this scatter interactively →