SELENOK

Across TCGA patient cohorts, SELENOK mutation is significantly associated with the RNA expression of many other genes, with 71 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SELENOK-associated genes across cancer lineages are RN7SL98P, NME1P1, and OR13K1P. Each is linked with SELENOK in more than 1 cancer types. Because this analysis shows association rather than direction, both SELENOK-to-partner and partner-to-SELENOK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL98P grouped by SELENOK-low versus SELENOK-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SELENOK→partner) and Y-score (partner→SELENOK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL98P →	+0.220	+3.845	<.001	.004	3	2
CESC	NME1P1 →	+0.067	+4.669	.009	.007	3	1
CESC	OR13K1P →	+0.046	+4.874	.007	.002	3	1
CESC	ATP6V0E1P3 →	+0.194	+4.653	.001	.004	3	1
CESC	RN7SKP209 →	+0.480	+5.569	<.001	.002	3	1
CESC	RNA5SP340 →	+0.392	+4.601	.002	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 71 associations by consensus.

RN7SL98P by SELENOK expression — UCEC

Explore this box plot interactively →