SELE

Across TCGA cell cohorts, SELE RNA expression is significantly associated with the go_rna of many other GO terms, with 342 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SELE-associated GO terms across cancer lineages are Cellular response to tumor necrosis factor, Golgi vesicle transport, and Positive regulation of mRNA metabolic process. Each is linked with SELE in more than 2 cancer types. Because this analysis shows association rather than direction, both SELE-to-partner and partner-to-SELE results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to tumor necrosis factor grouped by SELE-low versus SELE-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SELE→partner) and Y-score (partner→SELE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Cellular response to tumor necrosis factor →	+0.036	+0.020	.002	.008	3	3
SKIN	Golgi vesicle transport →	+0.032	+0.028	.003	.008	3	3
BLOOD_Leukemia	Positive regulation of mRNA metabolic process →	+0.054	+0.004	<.001	.008	3	3
BREAST	Type 2 mitophagy →	-0.113	-0.181	.006	.008	3	2
SKIN	Basement membrane organization →	+0.118	+0.038	<.001	.004	3	2
SKIN	Adenylate cyclase-activating G protein-coupled receptor signaling pathway →	-0.041	-0.020	.002	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 342 associations by consensus.

Cellular response to tumor necrosis factor by SELE expression — SKIN

Explore this box plot interactively →